How to Treat or Cure G6PD Deficiency

G6PD deficiency cannot be cured, because it is inherited. But most people live normally by avoiding triggers, and episodes of haemolysis can be treated.

Step 1: Confirm the diagnosis

A blood test measures G6PD enzyme activity. The test can look falsely normal during or soon after haemolysis, so it may be repeated after recovery. Family testing may be advised.

Step 2: Avoid triggers

• Fava beans
• High-risk medicines such as primaquine, dapsone, rasburicase and methylene blue
• Naphthalene mothballs
• Unchecked herbal products and supplements

Step 3: Tell your care team

Tell every doctor, dentist and pharmacist. Carry a list or card of medicines to avoid.

Step 4: Treat infections early

Seek care for fevers and illnesses, since infection is a common trigger. Use medicines that are safe in G6PD deficiency.

Step 5: If haemolysis occurs

• Stop the suspected trigger and see a doctor
• Fluids and rest
• Hospital care for severe anaemia, which may include a blood transfusion
• Phototherapy or exchange transfusion for newborns with high bilirubin

Step 6: Follow up

Recovery usually takes days to weeks. Your doctor may repeat blood counts and the enzyme test.

Step 7: Plan for the future

Genetic counselling can help families understand the risks.

What does not work

Herbs, tonics and supplements do not correct the enzyme deficiency.

Ayurvedic support

Ayurveda may support general wellbeing as an adjunct, but cannot treat the deficiency. Tell any practitioner you have G6PD deficiency.

Same-day care

Dark urine, yellow eyes, severe weakness or breathlessness need urgent assessment. Call 112 or 102 in an emergency.