Medicines and Products for Indigestion

Medicines can relieve indigestion, but they work best with lifestyle changes. Persistent symptoms need a doctor to find the cause.

Short-term relief

• Antacids (such as aluminium, magnesium or calcium compounds) neutralise acid for a short time. Use only occasionally.
• Alginates may help with reflux symptoms.
• Check with a pharmacist, as antacids can interact with other medicines.

Acid-lowering medicines

• H2 blockers such as famotidine
• Proton pump inhibitors (PPIs) such as omeprazole, pantoprazole and esomeprazole, usually for a few weeks, as advised
• Long-term PPI use needs a doctor's review, because of possible side effects such as low magnesium, low vitamin B12 and bone effects.

Treating the cause

• H. pylori: a combination of antibiotics and a PPI for 10 to 14 days, as prescribed. Finish the full course.
• Ulcers, gallstones, GERD or other causes are treated based on the diagnosis.
• Prokinetic medicines may be used for delayed stomach emptying.
• Low-dose antidepressants are sometimes used for functional dyspepsia under medical supervision.

Safety

• Avoid NSAID painkillers such as ibuprofen and diclofenac where possible. Ask your doctor about alternatives.
• Do not take acid-lowering medicines for months without advice.
• Seek care before using any medicine in pregnancy, or for children.

Herbal products

Evidence is limited. Do not use them to treat alarm symptoms.

Key point

Use medicines under medical guidance, and do not mask symptoms that persist.

Before your appointment

Note when symptoms started, how they relate to meals, and what makes them better or worse. List all medicines, especially painkillers, and any herbal products. Mention weight loss, vomiting, black stools, trouble swallowing, family history of stomach problems, smoking and alcohol. Ask about tests such as an H. pylori test or endoscopy, and the warning signs that mean you should call 112 or 102.