Medicines and products for psychosis

Antipsychotic medicines are the main treatment for psychosis. They must be prescribed and monitored by a psychiatrist.

Antipsychotics

• Second-generation (atypical): such as risperidone, olanzapine, quetiapine, aripiprazole and clozapine
• First-generation: such as haloperidol and chlorpromazine
• Long-acting injections: given every few weeks to months, to help people who find daily tablets difficult

They reduce hallucinations, delusions and agitation. They usually start to work within days to weeks, with full effect over weeks.

Other medicines

• Mood stabilisers and antidepressants when mood symptoms are present
• Short-term sedatives for severe agitation or sleep
• Medicines to ease side effects

Common side effects

• Drowsiness, weight gain, restlessness, stiffness and tremor
• Dry mouth and constipation
• Increased blood sugar and cholesterol
• Rare serious effects such as neuroleptic malignant syndrome or blood count changes with clozapine

Important cautions

• Never stop or change doses suddenly. Stopping is the most common cause of relapse.
• Tell the doctor about side effects, as dose or drug can be changed
• Avoid alcohol and drugs
• Do not take herbal products without telling your doctor
• Regular blood tests and health checks are needed

Therapy

• Cognitive behavioural therapy for psychosis
• Family therapy and support
• Social support and rehabilitation

Ayurvedic view (interpretive)

Herbal products are not a substitute for antipsychotics and can interact with them.

Remember

Antipsychotic medicines work best when taken regularly with follow-up. Do not stop them without medical advice.